Caprylic Acid in the purification of horse tetanus IgG immunoglobulin

Tetanus in the Horse

I regret having to write a letter of this nature to your fine publication. I am cer· tain that you want only accurate articles that conform to your high journalistic standards. I feel that it was unfortunate that my article , "Aplastic Anemia in a Cat," was published under that title in Vol. 33, No. 1 of the I.S.U. Veterinarian. The title was changed after the article was submitted and does not...

Tetanus in the horse

ANTI-TETANUS IMMUNOGLOBULIN ISOTYPES IN WOMEN OF CHILDBEARING AGE

Neonatal tetanus (NT) is a leading cause of neonatal mortality in many parts of the world. Tetanus is a vaccine-preventable disease and is second only to measles worldwide as a cause of childhood mortality. In this study the various irnrnunoglobulin classes of anti-tetanus antibody in the sera of 105 Iranian women of childbearing age (13-45 years) were titrated by enzyme linked immunosorben...

Preclinical Evaluation of Caprylic Acid-Fractionated IgG Antivenom for the Treatment of Taipan (Oxyuranus scutellatus) Envenoming in Papua New Guinea

BACKGROUND Snake bite is a common medical emergency in Papua New Guinea (PNG). The taipan, Oxyuranus scutellatus, inflicts a large number of bites that, in the absence of antivenom therapy, result in high mortality. Parenteral administration of antivenoms manufactured in Australia is the current treatment of choice for these envenomings. However, the price of these products is high and has incr...

Estimate of colostral immunoglobulin G concentration using refractometry without or with caprylic acid fractionation.

Our objectives were to evaluate the use of refractometry as a means of estimating immunoglobulin G (IgG) concentration of bovine maternal colostrum (MC) and determine if fractionation of MC using caprylic acid (CA) improved estimates of IgG. Samples (n=85) of MC were collected from a single dairy in California and used to determine the method of CA fraction that produced the best prediction of ...